Impact of Different Artificial Intelligence User Interfaces on Lung Nodule and Mass Detection on Chest Radiographs
2026-01-24https://doi.org/10.1148/atlas.1769269955302
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Overview
Schema Version
https://atlas.rsna.org/schemas/2025-11/model.json
Name
Impact of Different Artificial Intelligence User Interfaces on Lung Nodule and Mass Detection on Chest Radiographs
Link
https://dx.doi.org/10.1148/ryai.220079
Indexing
Keywords: Artificial Intelligence, Chest Radiograph, Conventional Radiography, Lung Nodule, Mass Detection
Content: CH
RadLex: RID10345, RID39056, RID50149
Author(s)
Jennifer S. N. Tang
Jeffrey K. C. Lai
John Bui
Wayland Wang
Paul Simkin
Dayu Gai
Jenny Chan
Diane M. Pascoe
Stefan B. Heinze
Frank Gaillard
Elaine Lui
Organization(s)
Department of Radiology, Royal Melbourne Hospital
Department of Radiology, University of Melbourne
Version
1.0
License
Text: © 2023 Radiological Society of North America, Inc.
Funding
Authors declared no funding for this work.
Ethical review
Approved by The Royal Melbourne Hospital Ethics Committee; case data were retrospectively collected and de-identified; patient consent waived; written informed consent obtained from all reader participants.
Date
Updated: 2023-05-01
Published: 2023-03-22
Created: 2022-04-25
References
[1] Tang JSN; Lai JKC; Bui J; Wang W; Simkin P; Gai D; Chan J; Pascoe DM; Heinze SB; Gaillard F; Lui E. "Impact of Different Artificial Intelligence User Interfaces on Lung Nodule and Mass Detection on Chest Radiographs". Radiology: Artificial Intelligence. 2023;5(3):e220079. 2023-03-22. doi:10.1148/ryai.220079. PMID: 37293345. PMCID: PMC10245182.
Model
Architecture
Commercial comprehensive deep-learning model for chest radiographs (Annalise.ai) producing 124 clinical findings; study varied user interface components (text, AI confidence score, image overlay).
Availability
Commercially available via Annalise.ai platform; demo interface customized for the study. https://annalise.ai/
Clinical benefit
When presented as text-only output, AI assistance significantly improved radiologist detection of lung nodules/masses on chest radiographs compared with no AI.
Clinical workflow phase
Clinical decision support during image interpretation.
Degree of automation
Assists radiologists with decision support (text output, optional confidence score and image overlay) without automating final diagnosis.
Indications for use
Assisting radiologists in detecting lung nodules and masses on chest radiographs in a hospital radiology setting.
Input
Chest radiograph images presented via a web-based interface.
Limitations
Single-center retrospective paired-reader study with small participant and case numbers; UI options limited to those available on a single proprietary software; potential selection bias; fixed limited viewing time per case (25 seconds) may have constrained use of more complex UIs; presence of other pathologies may have affected performance.
Output
CDEs: RDE1704.1, RDE1702.3
Description: Three UI variants of AI output: (a) text-only; (b) text + AI confidence score; (c) text + AI confidence score + image overlay (localization). Confidence score and overlay displayed only when AI predicted a positive finding.
Recommendation
UI selection for AI outputs should be validated against performance, not solely user preference.
Regulatory information
Comment: Per article, Annalise.ai chest radiograph algorithm has TGA and CE clearance.
Authorization status: Cleared (Therapeutic Goods Administration [Australia] and European CE marking) for the underlying Annalise.ai chest radiograph algorithm.
Use
Intended: Detection
User
Intended: Radiologist