Automated Surgical Intervention Support Tool for Traumatic Brain Injury (ASIST-TBI)
model2025-11-30https://doi.org/10.1148/atlas.1764460229714
153

Overview

Schema Version

https://atlas.rsna.org/schemas/2025-11/model.json

Name

Automated Surgical Intervention Support Tool for Traumatic Brain Injury (ASIST-TBI)

Link

https://doi.org/10.1148/ryai.230088

Indexing

Keywords: CT, Brain/Brain Stem, Surgery, Trauma, Prognosis, Classification, Traumatic Brain Injury, Triage, Machine Learning, Decision Support
Content: CT, ER, NR

Author(s)

Christopher W. Smith
Armaan K. Malhotra
Christopher Hammill
Derek Beaton
Erin M. Harrington
Yingshi He
Husain Shakil
Amanda McFarlan
Blair Jones
Hui Ming Lin
François Mathieu
Avery B. Nathens
Alun D. Ackery
Garrick Mok
Muhammad Mamdani
Shobhit Mathur
Jefferson R. Wilson
Robert Moreland
Errol Colak
Christopher D. Witiw

Organization(s)

St Michael's Hospital
Unity Health Toronto, Li Ka Shing Knowledge Institute
Unity Health Toronto, Data Science and Advanced Analytics
University of Toronto, Temerty Faculty of Medicine
University of Toronto, Institute for Health Policy, Management and Evaluation
University of Toronto, Interdepartmental Division of Critical Care
University of Toronto, Leslie Dan Faculty of Pharmacy
Sunnybrook Health Sciences Centre, Division of Trauma Surgery

Version

1.0

License

Text: © 2024 by the Radiological Society of North America, Inc.
URL: https://pubs.rsna.org/doi/10.1148/ryai.230088

Contact

ot.htlaehytinu@witiW.rehpotsirhC

Funding

Supported by St Michael's Hospital Medical Services Association Innovation Fund. E.C. supported by the Odette Professorship in Artificial Intelligence for Medical Imaging, St Michael's Hospital, Unity Health Toronto.

Ethical review

Institutional research ethics board approval was obtained; informed consent was waived due to impracticality, minimal risk, and safeguards in place.

Date

Published: 2024-01-10

References

[1] Smith CW, Malhotra AK, Hammill C, et al.. "Vision Transformer–based Decision Support for Neurosurgical Intervention in Acute Traumatic Brain Injury: Automated Surgical Intervention Support Tool". Radiology: Artificial Intelligence. 2024;6(2):e230088. 2024-01-10. doi:10.1148/ryai.230088. PMID: 38197796. PMCID: PMC10982820.

Model

Architecture

Vision Transformer-based model: CT scans split into fixed-size 1D patches with learnable spatial embeddings, passed through a transformer encoder (pretrained weights frozen), followed by a multilayer perceptron binary classification head.

Availability

Not publicly released; data provided by third parties (Ontario Trauma Registry, Unity Health Toronto).

Clinical benefit

Predicts need for acute neurosurgical intervention from initial trauma head CT to support triage and interfacility transfer prioritization, potentially improving resource allocation and patient care.

Clinical workflow phase

patients’ triage; clinical decision support systems.

Decision threshold

Binary decision obtained by thresholding the classifier output; specific threshold not reported.

Degree of automation

Assists clinician decision-making (decision support); does not automate clinical decisions.

Indications for use

Adults (≥18 years) presenting with acute traumatic brain injury undergoing noncontrast head CT in emergency/trauma settings to assess likelihood of neurosurgical intervention within 72 hours.

Input

Preprocessed noncontrast head CT scans (NIfTI after DICOM conversion; registered to a standard head CT template).

Instructions

Apply to acute, preoperative, noncontrast trauma head CT scans with adequate image quality; exclude postoperative, contrast-enhanced, duplicate navigation, and nondiagnostic motion scans; trained for adults ≥18 years; predictions pertain to interventions within 72 hours of scan acquisition.

Limitations

Single-center development and testing with scans from a single CT manufacturer; potential bias from surgeon-level decision making in the ground truth; 72-hour intervention label may miss delayed interventions; misclassifications noted in cases with low GCS and small-volume hemorrhage (ICP monitoring), cases later exhibiting hemorrhage expansion, depressed/open skull fractures, and cases with large hemorrhages but DNR/poor neurologic status; fairness testing showed no significant differences by age or sex but lower GCS among misclassified cases; external validation pending.

Output

CDEs: RDE2278, RDE2279, RDE1791.4, RDE1981.2, RDE1981
Description: Binary classification indicating whether neurosurgical intervention will be required within 72 hours of the acute trauma head CT.

Recommendation

Use as an adjunct for triage and decision support to prioritize transfers and neurosurgical consultation in acute TBI; clinical judgment and guidelines should prevail, especially in severe TBI with established care pathways.

Reproducibility

Preprocessing and model architecture described; pretrained transformer encoder with frozen weights; additional training parameters provided in Appendix S1; code and model weights not provided.

Use

Intended: Decision support, Triage
Out-of-scope: Prognosis, Decision support
Excluded: Decision support

User

Intended: Referring provider, Physician, Radiologist, Other