Detection Transformer (DETR) for detection, localization, and characterization of focal liver lesions on abdominal ultrasound
2026-01-24https://doi.org/10.1148/atlas.1769275897396
301
Overview
Schema Version
https://atlas.rsna.org/schemas/2025-11/model.json
Name
Detection Transformer (DETR) for detection, localization, and characterization of focal liver lesions on abdominal ultrasound
Link
https://gitlab.inria.fr/hdadoun/focal-liver-lesions-us
Indexing
Keywords: Focal liver lesion, Ultrasound, Liver, Detection, Localization, Characterization, Benign vs malignant, DETR, Transformer, Object detection
Content: US, GI, OI
Author(s)
Hind Dadoun
Anne-Laure Rousseau
Eric de Kerviler
Jean-Michel Correas
Anne-Marie Tissier
Fanny Joujou
Sylvain Bodard
Kemel Khezzane
Constance de Margerie-Mellon
Hervé Delingette
Nicholas Ayache
Organization(s)
Université Côte d’Azur, Inria, Epione Team
Georges Pompidou European Hospital APHP, Université de Paris
NHance.ngo
Hôpital Saint Louis APHP, Université de Paris
Université de Paris and Université de l’Hôpital Necker
Version
1.0
Contact
rf.airni@nuodad.dnih
Funding
Supported in part by the French government through the 3IA Côte d’Azur Investments in the Future project managed by ANR (ANR-19-P3IA-0002).
Ethical review
Institutional review board–approved retrospective multicenter study (IRB00011591); informed consent waived.
Date
Updated: 2022-02-16
Published: 2022-03-02
Created: 2021-04-23
References
[1] Dadoun H, Rousseau AL, de Kerviler E, Correas JM, Tissier AM, Joujou F, Bodard S, Khezzane K, de Margerie-Mellon C, Delingette H, Ayache N.. "Deep Learning for the Detection, Localization, and Characterization of Focal Liver Lesions on Abdominal US Images". Radiology: Artificial Intelligence. 2022;4(3):e210110.. 2022-03-02. doi:10.1148/ryai.210110. PMID: 35652113. PMCID: PMC9152842.
Model
Architecture
Detection Transformer (DETR) vision transformer–based end-to-end object detection network fine-tuned for ultrasound FLL detection, localization, and characterization.
Availability
All code used for this study: https://gitlab.inria.fr/hdadoun/focal-liver-lesions-us
Clinical benefit
Assists in screening by detecting and localizing focal liver lesions and characterizing them as benign or malignant on abdominal ultrasound images; performance matched or exceeded experts in several tasks, potentially aiding nonexpert caregivers.
Clinical workflow phase
Patients’ triage / screening decision support during ultrasound interpretation.
Decision threshold
Class-specific probability thresholds selected to maximize F1 score on validation; IOU threshold of 0.3 used to assign true positives for localization/classification.
Degree of automation
Automated detection, localization, and classification; supports clinician decision-making.
Indications for use
Image-based aid for detecting, localizing, and characterizing focal liver lesions on noncontrast B-mode abdominal ultrasound images of adult patients (≥18 years) in hospital settings.
Input
Preprocessed B-mode abdominal ultrasound images (JPEG converted from DICOM; US fan retained; text/graphics and biometric overlays removed).
Instructions
Apply to noncontrast B-mode abdominal US images after de-identification and fan/overlay removal as described. Use class-specific probability thresholds (chosen on validation) and IOU > 0.3 to consider matches. Intended for images similar to those from the two participating hospitals and vendors in the study.
Limitations
Retrospective study with small external test set (48 patients, 155 images). Reference standard for localization required unanimous adjudication, which may bias dataset and limit scalability. Poor-quality or uninterpretable images were excluded; performance on such images is unknown. Networks and experts were blinded to clinical context; real-world performance with clinical data may differ. Operator dependence of ultrasound may affect generalizability across sites/operators/vendors. Lower performance for cyst detection, likely due to class imbalance and confusion with vascular structures.
Output
CDEs: RDE65, RDE2077
Description: Bounding boxes for liver and focal liver lesions with labels indicating presence/absence of lesions, lesion malignancy (benign vs malignant), and benign/malignant subtypes (cyst, angioma, focal nodular hyperplasia, adenoma, metastasis, hepatocellular carcinoma).
Recommendation
Research-use decision support to assist nonexpert and expert users in screening for and assessing focal liver lesions on abdominal US images.
Reproducibility
Training details reported: 100 epochs; SGD with Nesterov momentum; learning rate 0.0048; batch size 4; momentum 0.9; weight decay 0.0001; warm-up first epoch; LR decay at epochs 75 and 90; data augmentation via learned bounding-box policies. Code repository provided.
Use
Intended: Detection and diagnosis
Out-of-scope: Diagnosis
Excluded: Image quality enhancement
User
Intended: Radiologist, Other, Caregiver